Novel collaborative study on Can1 transporter ubiquitylation via TORC1 published in International Journal of Molecular Sciences

A fruitful collaboration with the group of Dr. C. Gournas, former postdoc in the lab, led to publication of a novel article entitled “The Bul1/2 Alpha-Arrestins Promote Ubiquitylation and Endocytosis of the Can1 Permease upon Cycloheximide-Induced TORC1-Hyperactivation “ by Megarioti et al. . In this work, we dissected the mechanisms responsible for ubiquitylation and endocytosis of the yeast Can1 arginine transporter via arrestin-like adaptors under the control of “Target of Rapamycin Complex 1” (TORC1) in yeast.